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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ILKAP
All Species:
32.12
Human Site:
S37
Identified Species:
50.48
UniProt:
Q9H0C8
Number Species:
14
Phosphosite Substitution
Charge Score:
-0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9H0C8
NP_110395.1
392
42907
S37
D
D
L
P
P
A
S
S
T
D
S
G
S
G
G
Chimpanzee
Pan troglodytes
XP_001152781
553
60157
S200
D
D
L
P
P
A
S
S
T
D
S
G
S
G
G
Rhesus Macaque
Macaca mulatta
XP_001094705
590
64766
S237
D
D
L
P
P
A
S
S
T
D
S
G
S
G
G
Dog
Lupus familis
XP_543305
401
43921
S37
D
D
L
P
P
A
S
S
T
D
S
G
S
G
G
Cat
Felis silvestris
Mouse
Mus musculus
Q8R0F6
392
42756
S37
E
D
L
P
P
A
S
S
T
D
S
G
S
G
G
Rat
Rattus norvegicus
Q9Z1Z6
392
42726
S37
E
D
L
P
P
T
S
S
T
D
S
G
S
G
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513557
590
63726
S80
D
D
L
P
P
A
S
S
A
D
S
G
S
G
G
Chicken
Gallus gallus
XP_422661
389
42657
S34
D
D
L
P
P
A
G
S
A
D
T
G
K
G
S
Frog
Xenopus laevis
NP_001086890
344
37998
V18
P
R
A
P
G
P
A
V
S
P
S
E
A
G
P
Zebra Danio
Brachydanio rerio
NP_001082973
129
14081
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
NP_496370
242
26827
Sea Urchin
Strong. purpuratus
XP_001180671
354
39861
K25
S
A
N
T
Q
V
D
K
K
K
E
D
A
N
S
Poplar Tree
Populus trichocarpa
XP_002321498
266
28901
Maize
Zea mays
NP_001130289
360
39005
S27
I
K
G
T
D
T
A
S
E
T
G
D
S
V
E
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9LMT1
351
38467
S24
K
H
A
A
D
S
F
S
S
E
D
L
V
S
P
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
70.3
65
94.2
N.A.
95.1
95.1
N.A.
60.1
84.1
58.1
23.7
N.A.
N.A.
N.A.
28.8
47.7
Protein Similarity:
100
70.5
65.2
95.2
N.A.
97.6
96.9
N.A.
62.8
88.5
72.6
29.3
N.A.
N.A.
N.A.
42.5
65
P-Site Identity:
100
100
100
100
N.A.
93.3
86.6
N.A.
93.3
66.6
20
0
N.A.
N.A.
N.A.
0
0
P-Site Similarity:
100
100
100
100
N.A.
100
93.3
N.A.
93.3
73.3
40
0
N.A.
N.A.
N.A.
0
6.6
Percent
Protein Identity:
26.7
33.1
N.A.
32.4
N.A.
N.A.
Protein Similarity:
38.2
53.8
N.A.
52.8
N.A.
N.A.
P-Site Identity:
0
13.3
N.A.
6.6
N.A.
N.A.
P-Site Similarity:
0
20
N.A.
26.6
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
7
14
7
0
47
14
0
14
0
0
0
14
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
40
54
0
0
14
0
7
0
0
54
7
14
0
0
0
% D
% Glu:
14
0
0
0
0
0
0
0
7
7
7
7
0
0
7
% E
% Phe:
0
0
0
0
0
0
7
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
7
0
7
0
7
0
0
0
7
54
0
60
47
% G
% His:
0
7
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
7
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
7
7
0
0
0
0
0
7
7
7
0
0
7
0
0
% K
% Leu:
0
0
54
0
0
0
0
0
0
0
0
7
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
7
0
0
0
0
0
0
0
0
0
0
7
0
% N
% Pro:
7
0
0
60
54
7
0
0
0
7
0
0
0
0
14
% P
% Gln:
0
0
0
0
7
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
7
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
7
0
0
0
0
7
47
67
14
0
54
0
54
7
14
% S
% Thr:
0
0
0
14
0
14
0
0
40
7
7
0
0
0
0
% T
% Val:
0
0
0
0
0
7
0
7
0
0
0
0
7
7
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _